Chewing the fat
نویسندگان
چکیده
منابع مشابه
Chewing the Fat on Tumor Cell Metabolism
Tumor cells undergo a metabolic shift toward specific bioenergetic (glycolysis) and anabolic (protein and lipid synthesis) processes that promote rapid growth. Nomura et al. (2010) now demonstrate that an increase in monoacylglycerol lipase (MAGL) drives tumorigenesis through the lipolytic release and remodeling of free fatty acids.
متن کاملAutophagosomes and lipid droplets: no longer just chewing the fat.
Autophagosomes are organelles capable of sequestering and degrading diverse cytoplasmic cargo for nutritional and quality control purposes. Targeted are also lipid droplets (LDs), the cytoplasmic stores of neutral lipids. In this issue of The EMBO Journal, Shpilka et al (2015) show that the relationship between LDs and autophagosomes is far more intricate and that LDs regulate autophagosome bio...
متن کاملChewing the fat on natural killer T cell development
Natural killer T cells (NKT cells) are selected in the thymus by self-glycolipid antigens presented by CD1d molecules. It is currently thought that one specific component of the lysosomal processing pathway, which leads to the production of isoglobotrihexosylceramide (iGb3), is essential for normal NKT cell development. New evidence now shows that NKT cell development can be disrupted by a dive...
متن کاملComparison of the effect of chewing mastic and spearmint sugar-free chewing gum on salivary flow rate and pH
BACKGROUND AND AIM: Hyposalivation can cause many difficulties for patients like opportunistic infections such as candidiasis, mouth sores, and dysphagia as well as reduced quality of life (QOL). Methods such as using sugar-free chewing gum are recommended to treat this complication. Mastic is a natural substance and since it has various properties in addition ...
متن کاملChewing after stress: psychosocial stress influences chewing frequency, chewing efficacy, and appetite.
BACKGROUND Psychosocial stress is accompanied by an increase in the activity of the hypothalamic-pituitary-adrenocortical (HPA)-axis and by an increase in food intake. At present, no studies have been conducted to examine the impact of a potent laboratory stress test on the chewing frequency. METHODS Thirty-one healthy participants (14 females, mean age 27.13) were compared after they had ful...
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ژورنال
عنوان ژورنال: BMJ
سال: 2014
ISSN: 1756-1833
DOI: 10.1136/bmj.g2252